The simple start:
(1) Charge the battery.
NOTE: Don't let a battery get and stay discharged for long, because that causes what is called sulfation That is material forming on the plate and ending or at least reducing the battery's life.
(2) Disconnect the ground.
(3) Put a 12 volt test light between the ground cable and the negative terminal of the battery.
(4) If the light is on, something is completing a circuit, running down the battery. That could be a clock or radio, so you might want to disconnect it/them at the start of your tests (note where they go).
(5) If you want to be sure the test will work, and if the light is off, pull you headlight switch to an on position. The test light should light.
NOTE: Keep in mind, it only takes dropping a bit of power across a circuit to drain a battery, in time. As such, ONE of the most critical tools to have in your tool box is, a multimeter. It will detect and reveal what you cannot see with the test light.
(6) Start pulling fuses and watching the test light [or meter] until the meter no longer registers voltage or the light goes out.
(7) Don't forget there may be cobbled circuits from previous owners. They may or may not have fuses. If you're still showing a drain after pulling [and putting back] fuses, do a bunch more searching.
NOTE: Extra hot lines from the positive battery terminal or starter can give clues, if the simple tests don't give results.
OTHER SIDE NOTES:
* Years back, I worked on a car with a battery that was draining. The first thing I noticed was, the battery was filthy.
On a whim, I put a volt meter across the top of the battery and got about 12 volts. The dirt, debris and acids from the battery gassing mixed and produced a circuit.
I washed the top of the battery with a water and baking soda mix and the problem went away.
* My 78 battery kept dying in just a few days. The previous owner had wired the choke straight to the battery.