eh just like I said do what you want. Or I should say the Op can do what they want.
I like sticking to what I do. I normally don't use a sealer or final primer, I usually go right into paint after body work. Several I've done in a final prime, all over, but I always go with 400 or 600. I have done more 400's then I have 600's and was planning to do 600 on my truck only because of the metalics.
Like I said most is just general rules of thumb.
I've done my fair share of body work, paint and such, ever since I was 16 or so, it's been about 10-12 years now I guess and my old man has been at it for way more then me.
I just look at it as personal prefference.
you talk to any body man or painter, some are set in their ways and won't change, some will, some do only single stage and swear by it, sme say 2 stage or more. I see it alot and see it on everything, prep, sand, body work, paint etc.