Since you’re adding 4 subs, I’m assuming K5 or Suburban.
If K5, and assuming you remove the top, I’d highly recommend going ported.
Sealed boxes almost require the vehicle to have all 6 walls to help you feel the bass. Once you remove the top, open the windows, and 80 mph, bass goes “out the window”.
I only have 2 10s in a ported (38hz) enclosure and you still feel the bass.
When I designed my system, I was thinking about those wake boats you hear/feel on the lake.
I have two 3.5”, four 6.5”, two 6x9” and the two 10s ported. It gets the job done. Plus the subs are easily unplugged and removed if I need the extra room for a road trip.